Doctors info
Dr. Savitha S. Sharma

Dr. Savitha S. Sharma

MSc - Biochemistry, Ph.D - molecular Oncology (2013), Postdoctoral Fellow (Molecular Oncology) | Senior Scientist

13 years of experience
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Professional Overview

Dr. Savitha S. Sharma is a Senior Scientist in the Department of Molecular Oncology at Sri Shankara Cancer Hospital and Research Centre, Bengaluru. A trained cell and molecular biologist, she holds a PhD from Texas Tech University Health Sciences Center, USA (2007) and completed her postdoctoral fellowship at Moffitt Cancer Center, USA (2013), focusing on transcriptional regulation, cell-cycle control, and hematopoietic differentiation. She brings over 17 years of postdoctoral and translational research experience in the field of molecular oncology.

Her current research explores mechanisms underlying cancer initiation, progression, and therapy resistance, with a focus on transcriptional plasticity, radioresistance, and biomarker discovery for early detection. She employs cell-based models, patient-derived organoids, and in vivo systems, integrating cell biology, proteomics, genomics, and metabolomics approaches. She has received multiple research grants, including support from RGUHS, Lady Tata Memorial Trust, DST (Women Scientist-A), and the Bankhead-Coley Cancer Research Program (USA). She has published in reputed journals such as Oncogene, JBC, Cell Cycle, and Ageing.

Research Publications

1. The deubiquitylase USP7 is a novel cyclin F-interacting protein and regulates cyclin F protein stability

Authors: Sharma SS, Pledger WJ, Kondaiah P

Journal: Aging

Published: 2022

Additional Details: 14(21):8645-60

2. Enhanced co-expression of cyclin F and USP7 in luminal A breast cancer correlates with endocrine resistance, high oxidative phosphorylation, and low inflammatory signatures

Authors: Sharma SS, Hari PS, Nivedhitha R

Journal: bioRxiv

Published: 2026 Jan 8

Additional Details: 2026-01

3. Abstract P1-06-23: Extracellular matrix in Young Onset Breast Cancer–A dynamic niche as a therapeutic target

Authors: Kanyadhara LK, BS S, Srihari S, Hari PS, Veeraiyan D, Choudhary V, Zeleke WE, Sharma SS, Sarvothama M, Shetty K, Bhatt R

Journal: Clinical Cancer Research

Published: 2025 Jun 13

Additional Details: 31(12_Supplement):P1-06

4. Development and characterization of novel Schiff base-thiazole derivatives: Exploring antimicrobial activity through spectroscopic analysis, DFT calculations, and molecular docking studies

Authors: Sharma M, Savita S, Wadhwa K, Mishra V, Javed S, Ranjan KR, Rathi AK, Kaur H

Journal: Journal of Molecular Structure

Published: 2025 Jun 5

Additional Details: 1331:141568

Languages Spoken

Kannada English Hindi Tulu
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