Doctors info

Professional Overview

Dr. Rekha V. Kumar is Senior Consultant and Emeritus Professor in the Department of Histopathology at Sri Shankara Cancer Hospital and Research Centre, Bengaluru. With nearly 40 years of experience in oncopathology, she has previously served as Professor and Head of Pathology at Kidwai Memorial Institute of Oncology, where she led diagnostic units including histopathology, cytopathology, haematology, and cytogenetics. She earned her MBBS from CMC Vellore and MD in Pathology from Bangalore University.

A recipient of the UICC fellowship at Johns Hopkins University, she has taught MD, DNB, and fellowship students, guided PhD scholars under RGUHS, and published over 130 peer-reviewed papers. Her diagnostic focus spans head and neck, bone and soft tissue, breast, gynecologic, and gastrointestinal cancers. She is actively involved in molecular pathology and envisions wider integration of AI-driven diagnostics. She continues to play a central role in oncopathology education, research, and precision cancer diagnostics.

Research Publications

1. Downregulation of Decorin in ovarian cancer cells and colonization microenvironment drives progression

Authors: Sarkar P, Naha A, Hussain S, Manattayil JK, PS H, Korlimarla A, Vadaparty A, Raghunathan V, Kumar R, Bhat R

Journal: Biointerphases

Published: 2025 Sep 1

Additional Details: 20(5)

2. Novel Gene expression-based Risk Stratification tool predicts recurrence in Non-muscle invasive Bladder cancer

Authors: HP S, Paul L, Veeraiyan D, Narikot A, Veldore V, Tanwar N, Goswami H, Kumar RV, SB S, Korlimarla A

3. Novel Gene expression-based Risk Stratification tool predicts recurrence in Non-muscle invasive Bladder cancer

Authors: Srivatsa N, Hari PS, Rahul P, Paul L, Veeraiyan D, Narikot A, Veldore V, Tanwar N, Srikanthreddy P, Goswami H, Kumar RV

4. Lower expressions of MIR34a and MIR31 in colo-rectal cancer are associated with an enriched immune microenvironment

Authors: Naskar S, Mishra I, Srinath BS, Kumar RV, Devi D, Melgiri P, Hari PS, Sashtry M, Venkatachala K, Korlimarla A

Journal: Pathology-Research and Practice

Published: 2024 Oct 14

Additional Details: 155656

5. Syringocystadenocarcinoma Papilliferum of Thigh—a Rare Cutaneous Malignancy with Unusual Histology and Clinical Presentation.

Authors: Naskar S, Manohar A, H. G. S, V. D, Kumar RV, Srinath BS

Journal: Indian J Surg Oncol

Published: 2023

Additional Details: 14(4):900–3

6. Plasma Cell Neoplasm with Clear Cell Morphology—A Diagnostic Dilemma

Authors: Naskar S, Kumar RV

Journal: Indian J Med Paediatr Oncol

Published: 2023

Additional Details: s-0043-1770786

7. Molecular Characterization of Esophageal Squamous Cell Carcinoma Using Quantitative Proteomics

Authors: Mangalaparthi KK, Patel K, Khan AA, Nair B, Kumar RV, Prasad TSK, et al

Journal: Cancers

Published: 2023

Additional Details: 15(13):3302

8. Accuracy of high-risk HPV DNA PCR, p16(INK4a) immunohistochemistry or the combination of both to diagnose HPV-driven oropharyngeal cancer

Authors: Simoens C, Gheit T, Ridder R, Gorbaslieva I, Holzinger D, Lucas E, et al

Journal: BMC Infect Dis

Published: 2022

Additional Details: 22(1):676

9. miR-18a Mediates Immune Evasion in ER-Positive Breast Cancer through Wnt Signaling.

Authors: Nair, M.G.; D, Apoorva; M, Chandrakala; VP,Snijesh.; Patil, S.; CE, Anupama; Mukherjee, G.; Kumar, R.V.; Prabhu, J.S.; TS, Sridhar

Journal: Cells

Published: 2022

Additional Details: 11(10):1672

10. PD-1 and PD-L1 Expression in Indian Women with Breast Cancer

Authors: Bharadwaj KR, Dasgupta K, Narayana SM, Ramachandra C, Babu SMC, Rangarajan A, Kumar R V

Journal: EJBH

Published: 2022

Additional Details: 18(1):21–9

11. Infrared Microspectroscopy With Multivariate Analysis to Differentiate Oral Hyperplasia From Squamous Cell Carcinoma: A Proof of Concept for Early Diagnosis

Authors: Kuhar N, Nazeer SS, Kumar RV, Mukherjee G, Umapathy S

Journal: Lasers Surg Med

Published: 2021

Additional Details: 53(10):1435–45

12. HPV DNA genotyping, HPV E6*I mRNA detection, and p16INK4a/Ki-67 staining in Belgian head and neck cancer patient specimens, collected within the HPV-AHEAD study

Authors: Simoens C, Gorbaslieva I, Gheit T, Holzinger D, Lucas E, Ridder R, et al

Journal: Cancer Epidemiology

Published: 2021

Additional Details: 72:101925

13. Role of Human Papillomavirus Infection in Head and Neck Cancer in Italy: The HPV-AHEAD Study

Authors: Tagliabue M, Mena M, Maffini F, Gheit T, Quirós Blasco B, Holzinger D, et al

Journal: Cancers

Published: 2020

Additional Details: 12(12):3567

14. Mutational Landscape of Esophageal Squamous Cell Carcinoma in an Indian Cohort.

Authors: Mangalaparthi KK, Patel K, Khan AA, Manoharan M, Karunakaran C, Murugan S, Gupta R,Khanna-Gupta A, Chaudhuri A,Kumar P, Nair B, Kumar RV,et al.

Journal: Front Oncol

Published: 2020

Additional Details: 10:1457

15. Systemic mastocytosis associated with Hodgkin’s lymphoma in a 4‐year‐old child

Authors: Srinivas SM, Agarwal R, Babu N, Naik M, Kumar R, Dhar S

Journal: Pediatric Dermatology

Published: 2020

Additional Details: 37(4):713–5

16. Phosphoproteomic analysis identifies CLK1 as a novel therapeutic target in gastric cancer.

Authors: Babu N, Pinto SM, Biswas M, Subbannayya T, Rajappa M, Mohan SV, Advani J, Rajagopalan P, Sathe G, Syed N, Radhakrishna VD, Muthusamy O, Navani S, Kumar RV, et al.

Journal: Gastric Cancer

Published: 2020

Additional Details: 23(5):796–810

17. Primary Gastric Synovial Sarcoma in a Child: A Case Report and Review of the Literature

Authors: Manohar A, Gopal C, Premalata CS, Kumar RV, Patil Okaly GV, Somashekhar SP, et al

Journal: Journal of Pediatric Hematology/Oncology

Published: 2021

Additional Details: 43(1):e119–22

18. FISH and HER2/neu equivocal immunohistochemistry in breast carcinoma

Authors: Patil Okaly G, Panwar D, Lingappa K, Kumari P, Anand A, Kumar P, Chikkalingaiah MH, Kumar RV

Journal: Indian J Cancer

Published: 2019

Additional Details: 56(2):119

19. Biological tailoring of adjuvant radiotherapy in head and neck and oral malignancies – The potential role of p53 and eIF4E as predictive parameters

Authors: Joseph B, Kumar RV, Champaka G, Shenoy A, Sabitha K, Lokesh V, et al

Journal: Indian J Cancer

Published: 2019

Additional Details: 56(4):330

20. Iduronate-2-Sulfatase-Regulated Dermatan Sulfate Levels Potentiate the Invasion of Breast Cancer Epithelia through Collagen Matrix

Authors: Singh V, Jha KK, KM Jyothsna, Kumar RV, Raghunathan V, Bhat R

Journal: JCM

Published: 2019

Additional Details: 8(10):1562

21. Is there difference between anastomotic site and remnant stump carcinoma in gastric stump cancers?—a single institute analysis of 90 patients

Authors: Chowdappa R, Tiwari AR, Ranganath N, Kumar RV

Journal: J Gastrointest Oncol

Published: 2019

Additional Details: 10(2):307–13

22. The eukaryotic initiation factor 4E (eIF4E) as a predictive biomarker in the negative margins of resected head and neck and oral cancers: Is there a role for tailoring adjuvant radiotherapy.

Authors: Joseph B, Kumar RV, Champaka G, Shenoy A, Sabitha KS

Journal: IJPO

Published: 2019

Additional Details: 6(1):47–51

23. Conjunctival melanoma with conjunctival melanocytic intraepithelial neoplasia in a patient with neurofibromatosis type 1

Authors: Sreelakshmi S, Divya V, Goswami M, Walvekar PV, Kumar RV

Journal: Journal of Diagnostic and Academic Pathology

Published: 2024 Jul 1

Additional Details: 1(2):86-8

24. The prognostic significance of the ‘Worst Pattern of Invasion’in oral cancers− an international collaborative multicentre analysis

Authors: Roy P, Weber MB, Gupta R, Kakkar A, Fonseca D, Bal M, Kamboj M, Anand N, Anila KR, Velusamy S, Uppin MS

Journal: Oral Oncology

Published: 2026 Mar 1

Additional Details: 174:107874

25. Novel Gene expression-based Risk Stratification tool predicts recurrence in Non-muscle invasive Bladder cancer

Authors: PS H, Paul L, Veeraiyan D, Narikot A, Veldore V, Tanwar N, Sreekanthreddy P, Goswami H, Kumar RV, Srinath BS, Korlimarla A

Journal: BMC cancer

Published: 2025 Dec

Additional Details: 25(1):1-0

26. Stromal LOX–FAK–β-catenin pathway locks mammary fibroblasts into a tumor-promoting myCAF state

Authors: Gandhi A, Beri D, Pally D, Manjunath S, Humcha S, Rangarajan A, Kumar RV, Bhat R, Tatu U, Kondaiah P

Journal: bioRxiv

Published: 2025 Jul 17

Additional Details: 2025-07

27. Prognostic significance of tumour–stroma ratio in prostatic adenocarcinoma: An analysis of radical prostatectomy specimens

Authors: Vijayanarasimha D, Archana M, Srivatsa N, Kumar RV

Journal: Journal of Diagnostic and Academic Pathology

Published: 2025 Jul 1

Additional Details: 2(2):74-8

28. Solitary fibrous tumour: A case series of a deceptively simple neoplasm in a tertiary care centre in South India

Authors: Rambhojun HD, Vijayanarasimha D, Velusamy S, Srihari SM, Venkataswamy C, Kumar RV, Srivatsa HG, Simha V, Srinath BS

Journal: Journal of Diagnostic and Academic Pathology

Published: 2025 Jul 1

Additional Details: 2(2):79-84

Languages Spoken

Kannada English Hindi

Dr. Rekha V. Kumar

Professional Overview

Research Publications

1. Downregulation of Decorin in ovarian cancer cells and colonization microenvironment drives progression

2. Novel Gene expression-based Risk Stratification tool predicts recurrence in Non-muscle invasive Bladder cancer

3. Novel Gene expression-based Risk Stratification tool predicts recurrence in Non-muscle invasive Bladder cancer

4. Lower expressions of MIR34a and MIR31 in colo-rectal cancer are associated with an enriched immune microenvironment

5. Syringocystadenocarcinoma Papilliferum of Thigh—a Rare Cutaneous Malignancy with Unusual Histology and Clinical Presentation.

6. Plasma Cell Neoplasm with Clear Cell Morphology—A Diagnostic Dilemma

7. Molecular Characterization of Esophageal Squamous Cell Carcinoma Using Quantitative Proteomics

8. Accuracy of high-risk HPV DNA PCR, p16(INK4a) immunohistochemistry or the combination of both to diagnose HPV-driven oropharyngeal cancer

9. miR-18a Mediates Immune Evasion in ER-Positive Breast Cancer through Wnt Signaling.

10. PD-1 and PD-L1 Expression in Indian Women with Breast Cancer

11. Infrared Microspectroscopy With Multivariate Analysis to Differentiate Oral Hyperplasia From Squamous Cell Carcinoma: A Proof of Concept for Early Diagnosis

12. HPV DNA genotyping, HPV E6*I mRNA detection, and p16INK4a/Ki-67 staining in Belgian head and neck cancer patient specimens, collected within the HPV-AHEAD study

13. Role of Human Papillomavirus Infection in Head and Neck Cancer in Italy: The HPV-AHEAD Study

14. Mutational Landscape of Esophageal Squamous Cell Carcinoma in an Indian Cohort.

15. Systemic mastocytosis associated with Hodgkin’s lymphoma in a 4‐year‐old child

16. Phosphoproteomic analysis identifies CLK1 as a novel therapeutic target in gastric cancer.

17. Primary Gastric Synovial Sarcoma in a Child: A Case Report and Review of the Literature

18. FISH and HER2/neu equivocal immunohistochemistry in breast carcinoma

19. Biological tailoring of adjuvant radiotherapy in head and neck and oral malignancies – The potential role of p53 and eIF4E as predictive parameters

20. Iduronate-2-Sulfatase-Regulated Dermatan Sulfate Levels Potentiate the Invasion of Breast Cancer Epithelia through Collagen Matrix

21. Is there difference between anastomotic site and remnant stump carcinoma in gastric stump cancers?—a single institute analysis of 90 patients

22. The eukaryotic initiation factor 4E (eIF4E) as a predictive biomarker in the negative margins of resected head and neck and oral cancers: Is there a role for tailoring adjuvant radiotherapy.

23. Conjunctival melanoma with conjunctival melanocytic intraepithelial neoplasia in a patient with neurofibromatosis type 1

24. The prognostic significance of the ‘Worst Pattern of Invasion’in oral cancers− an international collaborative multicentre analysis

25. Novel Gene expression-based Risk Stratification tool predicts recurrence in Non-muscle invasive Bladder cancer

26. Stromal LOX–FAK–β-catenin pathway locks mammary fibroblasts into a tumor-promoting myCAF state

27. Prognostic significance of tumour–stroma ratio in prostatic adenocarcinoma: An analysis of radical prostatectomy specimens

28. Solitary fibrous tumour: A case series of a deceptively simple neoplasm in a tertiary care centre in South India

Languages Spoken

Book Appointment