Doctors info
Dr. Karthik N. Rao

Dr. Karthik N. Rao

MBBS, MS, MCh (Head Neck Surgery and Oncology), FHNS, FACS, FAHNS, eFASCO, DEBEORLHNS

8 years of experience
Book Appointment

Professional Overview

Dr. Karthik N. Rao is Consultant and Head, Department of Head and Neck Surgical Oncology. He is a gold medalist in MS (Otorhinolaryngology) and M.Ch (Head and Neck Surgery and Oncology) from AIIMS, trained at Tata Memorial Hospital and is a Fellow of the American College of Surgeons (FACS), American Head and Neck Society (FAHNS), and a Diplomate of the European Board of Otorhinolaryngology. With over 8 years of clinical experience, he specializes in complex head and neck cancer surgeries, skull base procedures, and reconstructive oncology.

He serves as International Co-Chair of the Skull Base Section of AHNS and is Editor at Scientific Reports (Nature). He has authored 98 PubMed-indexed publications, 11 textbook chapters, and edited the Atlas of Head, Neck, and Skull Base Surgery. His clinical and research focus includes AI in oncology, collaborative trials, and surgical innovation, with a strong commitment to advancing global standards in head and neck cancer care.

Research Publications

1. Head and Neck Cancer Salvage Surgery in the Era of Immunotherapy and Beyond: A Review

Authors: Saba NF, Zalaquett NG, Rashid S, Rao KN, Takes RP, Bradford C, de Bree R, Beitler JJ, Forastiere AA, Vermorken JB, Hammond AL

Journal: JAMA Otolaryngology–Head & Neck Surgery

Published: 2025 Nov

2. Head and Neck Cancer Salvage Surgery in the Era of Immunotherapy and Beyond: A Review

Authors: Saba NF, Zalaquett NG, Rashid S, Rao KN, Takes RP, Bradford C, de Bree R, Beitler JJ, Forastiere AA, Vermorken JB, Hammond AL

Journal: JAMA Otolaryngology–Head & Neck Surgery

Published: 2025 Nov

3. Versatility of Islanded Nasolabial Flap Based on Facial Artery and Vein for Reconstruction of Oral Cancer Defects, Experience in a Tertiary Care Center

Authors: Mishra JK, Sahu SA, Arora RD, Sindhuja A, Rao KN

Journal: Indian Journal of Otolaryngology and Head & Neck Surgery

Published: 2024 Oct

Additional Details: 76(5):3944-50

4. Micrometastasis and Isolated Tumor Cells in Oral Squamous Cell Carcinoma: Refining Nodal Staging with Emerging Technologies

Authors: Mp S, Rao KN, Thompson LD, Rodrigo JP, de Bree R, Stenman G, Schilling C, Rinaldo A, Robbins KT, Nadal A, Agaimy A

Journal: Head and Neck Pathology

Published: 2025 Dec

Additional Details: 19(1):1-6

5. The Limitations of Artificial Intelligence in Head and Neck Oncology.

Authors: Rao KN, Fernandez-Alvarez V, Guntinas-Lichius O, Sreeram MP, de Bree R, Kowalski LP, Forastiere A, Pace-Asciak P, Rodrigo JP, Saba NF, Ronen O

Journal: Advances in therapy

Published: 2025 Jun

Additional Details: 42(6):2559-68

6. Targeted Screening Strategies for Head and Neck Cancer: A Global Review of Evidence, Technologies, and Cost-Effectiveness

Authors: Guntinas-Lichius O, Bücking C, Ng SP, López F, Rodrigo JP, Rao KN, Pelaz AC, Kowalski LP, Piazza C, Rinaldo A, Ferlito A

Journal: Diagnostics

Published: 2025 Aug 20

Additional Details: 15(16):2095

7. Global Incidence and Mortality of Myocardial Infarction in Multi-Modality Head and Neck Cancer Treatment: A Systematic Review and Meta-analysis.

Authors: Asarkar AA, Vasudevan SS, Fernandez-Alvarez V, Vermorken JB, Álvarez FL, Rao KN, Saba NF, de Bree R, Suárez C, Eisbruch A, Nuyts S

Journal: Advances in Therapy

Published: 2025 Aug 4

Additional Details: 1-29

8. Implication of surgical loupes on complications following thyroidectomy: a meta-analysis

Authors: Rao KN, Zafereo M, Rao AN, Nixon I, Robbins KT, Sreeram MP, Rodrigo JP, Sanabria A, Mair M, Vander Poorten V, Guntinas-Lichius O

Journal: European Archives of Oto-Rhino-Laryngology

Published: 2025 Mar

Additional Details: 282(3):1159-69

9. Thermo physical, spectroscopic and computational investigation of binary liquid mixtures at various temperatures and correlation with the Jouyban–Acree model (allyl alcohol, ethanoic acid, propanoic acid, and butanoic acid)

Authors: Narasimha Rao K, Paul Douglas S, Ramanjaneyulu E, Ravikumar S, Karthik R

Journal: Physics and Chemistry of Liquids

Published: 2025 May 4

Additional Details: 63(3):305-24

10. Endoscopic luminal restoration in complete esophageal obstruction: antegrade freehand technique

Authors: Pemmada V, Ramesh NK, Jain PK

Journal: Clinical endoscopy

11. Superficial Ulnar Artery Mimicking the Radial Artery During Radial Forearm Free Flap Harvest: A Surgical Pitfall and its Intraoperative Identification–A Case Report

Authors: Kapahtia R, Dange P, Rao KN, Sreeram MP, Srinath BS

Journal: Indian Journal of Otolaryngology and Head & Neck Surgery

Published: 2025 Apr 5

Additional Details: 1-4

12. The Chimeric Antero-Lateral Thigh Flap and Vastus Lateralis Muscle Flap for the Infratemporal Fossa Reconstruction in Oral Cancer Defects

Authors: Kapahtia R, Rao KN, P SM, Subramanium N, Srinath BS

Journal: Indian Journal of Otolaryngology and Head & Neck Surgery

Published: 2025 Feb

Additional Details: 77(2):897-904

13. Evidence Based Recommendations in Sinonasal Tumors Involving Orbit: Preservation or Exenteration? An IHNSG Guidelines.

Authors: Rao KN, Piazza C, Snyderman C, Vander Poorten V, Sreeram MP, Strojan P, Hanna E, Guntinas-Lichius O, Lopez F, Mikkelsen LH, Suárez C

Journal: Advances in Therapy

Published: 2025 Feb 6

Additional Details: 1-28

14. The Oncological Outcome of Postoperative Radiotherapy in Patients with Node-Negative Early-Stage (T1/T2/N0) Oral Squamous Cell Carcinoma and Perineural Invasion: A Meta-Analysis

Authors: Rao KN, Sreeram MP, de Bree R, Mendenhall WM, Strojan P, Stenman G, Mäkitie A, Nadal A, Rodrigo JP, Ng SP, Corry J

Journal: Cancers

Published: 2025 Mar 3

Additional Details: 17(5):862

15. Patterns of Lateral Lymph Node Involvement by Neck Level in cNIb Differentiated Thyroid Carcinoma: A Systematic Review and Meta-Analysis

Authors: Hartl DM, Rao KN, Coca Pelaz A, Rinaldo A, Zafereo ME, Randolph GW, Nixon IJ, Hamoir M, Robbins KT, Kowalski LP, Asciak PP

Journal: Diagnostics

Published: 2025 Jan

16. Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP): what do we need to know?

Authors: Coca-Pelaz A, Rodrigo JP, Agaimy A, Hartl DM, Stenman G, Vander Poorten V, Mäkitie AA, Zafereo M, Rao KN, Randolph GW, Rinaldo A

Journal: Virchows Archiv

Published: 2024 Dec

Additional Details: 485(6):977-87

17. Prognostic Effectiveness of PD-L1 Tumoral Expression in Oral Cavity Squamous Cell Carcinoma

Authors: Singh A, Nagarkar NM, Chowhan AK, Mehta R, Arora RD, Rao KN, Dange PS

Journal: Indian Journal of Surgical Oncology

Published: 2024 Dec

Additional Details: 15(4):816-24

18. Role of the FDG PET CT Scan in Pretreatment Evaluation of Oral Carcinomas

Authors: Banjare AK, Arora RD, Ravina M, Prajwal SD, Rao KN, Nagarkar NM

Journal: Indian Journal of Otolaryngology and Head & Neck Surgery

Published: 2024 Dec

Additional Details: 76(6):5346-52

19. Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP): what do we need to know?

Authors: Coca-Pelaz A, Rodrigo JP, Agaimy A, Hartl DM, Stenman G, Vander Poorten V, Mäkitie AA, Zafereo M, Rao KN, Randolph GW, Rinaldo A

Journal: Virchows Archiv

Published: 2024 Oct 23

Additional Details: 1-1

20. Implication of surgical loupes on complications following thyroidectomy: a meta-analysis

Authors: Rao KN, Zafereo M, Rao AN, Nixon I, Robbins KT, Sreeram MP, Rodrigo JP, Sanabria A, Mair M, Vander Poorten V, Guntinas-Lichius O

Journal: European Archives of Oto-Rhino-Laryngology

Published: 2024 Oct 7

Additional Details: 1-1

21. Alcohol-containing mouthwash and the risk of oral cancer: exploring the association

Authors: Rao KN, Mehta R, Dange P, Nagarkar NM

Journal: Indian Journal of Surgical Oncology

Published: 2024 Sep

Additional Details: 15(3):553-6

22. Trotter Procedure with Harmonic Scalpel: A Unique Approach to Mucoepidermoid Carcinoma of Tongue Base Revisited

Authors: Grover H, Arora RD, John RM, Rao KN, Nagarkar NM

Journal: Indian Journal of Otolaryngology and Head & Neck Surgery

Published: 2024 Oct

Additional Details: 76(5):4735-9

23. Biomaterial-Based Hemostasis: A Review of the Clinical and Functional Versatility of Oxidized Regenerated Cellulose

Authors: Kanagal D, Rao K, Gathoga P, Moharana K, Patil R, Jaiswal P, AP V, TS D, Patil Sr R

Journal: Cureus

Published: 2025 Oct 14

Additional Details: 17(10)

24. Alcohol-containing mouthwash and the risk of oral cancer: exploring the association

Authors: Rao KN, Mehta R, Dange P, Nagarkar NM

Journal: Indian Journal of Surgical Oncology

Published: 2024 Sep

Additional Details: 15(3):553-6

25. Role of the FDG PET CT Scan in Pretreatment Evaluation of Oral Carcinomas

Authors: Banjare AK, Arora RD, Ravina M, Prajwal SD, Rao KN, Nagarkar NM

Journal: Indian Journal of Otolaryngology and Head & Neck Surgery

Published: 2024 Aug 24

Additional Details: 1-7

26. Artificial neural network to predict post-operative hypocalcemia following total thyroidectomy

Authors: Rao KN, Arora R, Rajguru R, Nagarkar NM

Journal: Indian Journal of Otolaryngology and Head & Neck Surgery

Published: 2024 Aug

Additional Details: 76(4):3094-102

27. Assessment of the risk of malignancy in Bethesda III thyroid nodules: a comprehensive review

Authors: Rao KN, Randolph GW, Lopez F, Zafereo M, Coca-Pelaz A, Piazza C, Dange P, Rodrigo JP, Stenman G, de Keizer B, Nixon I

Journal: Endocrine

Published: 2024 Aug

Additional Details: 85(2):473-92

28. Topical Antibiotic-Induced Otomycosis-a Systematic Review of Aetiology and Risk Factors

Authors: Pereira M, Rao K, Sharin F, Tanweer F, Mair M, Rea P

Journal: Indian Journal of Otolaryngology and Head & Neck Surgery

Published: 2024 Oct

Additional Details: 76(5):3766-76

29. Misconducts in research and methods to uphold research integrity

Authors: Rao KN, Mair M, Arora RD, Dange P, Nagarkar NM

Journal: Indian Journal of Cancer

Published: 2024 Apr 1

Additional Details: 61(2):354-9

30. Primary management of operable locally advanced oral cavity squamous cell carcinoma: current concepts and strategies

Authors: Asarkar AA, Chang BA, de Bree R, Kowalski LP, Guntinas-Lichius O, Bradley PJ, de Graaf P, Strojan P, Rao KN, Mäkitie AA, López F

Journal: Advances in Therapy

Published: 2024 Jun

Additional Details: 41(6):2133-50

31. Trotter Procedure with Harmonic Scalpel: A Unique Approach to Mucoepidermoid Carcinoma of Tongue Base Revisited

Authors: Grover H, Arora RD, John RM, Rao KN, Nagarkar NM

Journal: Indian Journal of Otolaryngology and Head & Neck Surgery

Published: 2024 Jun 21

Additional Details: 1-5

32. Prognostic Effectiveness of PD-L1 Tumoral Expression in Oral Cavity Squamous Cell Carcinoma

Authors: Singh A, Nagarkar NM, Chowhan AK, Mehta R, Arora RD, Rao KN, Dange PS

Journal: Indian Journal of Surgical Oncology

Published: 2024 Jun 26

Additional Details: 1-9

33. Alcohol-Containing Mouthwash and the Risk of Oral Cancer: Exploring the Association

Authors: Rao KN, Mehta R, Dange P, Nagarkar NM

Journal: Indian Journal of Surgical Oncology

Published: 2024 May 8

Additional Details: 1-4

34. Versatility of Islanded Nasolabial Flap Based on Facial Artery and Vein for Reconstruction of Oral Cancer Defects, Experience in a Tertiary Care Center

Authors: Mishra JK, Sahu SA, Arora RD, Sindhuja A, Rao KN

Journal: Indian Journal of Otolaryngology and Head & Neck Surgery

Published: 2024 May 16

Additional Details: 1-7

35. Primary Management of Operable Locally Advanced Oral Cavity Squamous Cell Carcinoma: Current Concepts and Strategies

Authors: Asarkar AA, Chang BA, de Bree R, Kowalski LP, Guntinas-Lichius O, Bradley PJ, de Graaf P, Strojan P, Rao KN, Mäkitie AA, López F

Journal: Advances in therapy

Published: 2024 Apr 20

Additional Details: 1-8

36. Artificial neural network to predict post-operative hypocalcemia following total thyroidectomy

Authors: Rao KN, Arora R, Rajguru R, Nagarkar NM

Journal: Indian Journal of Otolaryngology and Head & Neck Surgery

Published: 2024 Mar 25

Additional Details: 1-9

37. Assessment of the risk of malignancy in Bethesda III thyroid nodules: a comprehensive review

Authors: Rao KN, Randolph GW, Lopez F, Zafereo M, Coca-Pelaz A, Piazza C, Dange P, Rodrigo JP, Stenman G, de Keizer B, Nixon I

Journal: Endocrine

Published: 2024 Feb 28

Additional Details: 1-20

38. Lower rates of hypocalcemia following near-infrared autofluorescence use in thyroidectomy: a meta-analysis of RCTs

Authors: Rao KN, Rajguru R, Dange P, Vetter D, Triponez F, Nixon IJ, Randolph GW, Mäkitie AA, Zafereo M, Ferlito A

Journal: Diagnostics

Published: 2024 Feb 27

Additional Details: 14(5):505

39. Lower Rates of Hypocalcemia Following Near-Infrared Autofluorescence Use in Thyroidectomy: A Meta-Analysis of RCTs

Authors: Rao KN*, Rajguru R, Dange P, Vetter D, Triponez F, Nixon IJ, Randolph GW, Mäkitie AA, Zafereo M, Ferlito A

Journal: Diagnostics

Published: 2024

Additional Details: 14(5):505

40. Comparing Mohs micrographic surgery and wide local excision in the management of head and neck dermatofibrosarcoma protuberans: a scoping review

Authors: Sanabria A, Pinillos P, Chiesa-Estomba C, Guntinas-Lichius O, Kowalski LP, Mäkitie AA, Rao KN, Ferlito A

Journal: J Dermatolog Treat

Published: 2024 Dec

Additional Details: 35(1):2295816

41. A meta-analysis of surgical outcomes of T4a and infranotch T4b oral cancers

Authors: Rao KN, Arora R, Dange P, Nagarkar N, Mäkitie AA, Kowalski LP, Eisbruch A, Hamoir M, Civantos FJ, Vander Poorten V, Ng SP

Journal: Oncology and therapy

Published: 2023 Dec

Additional Details: 11(4):461-80

42. Pharyngocutaneous Fistula after Laryngectomy: An Umbrella Systematic Review to Uncover Lacunae in Meta-Analyses

Authors: Rao KN*, Arora R, Singh A, Dange P, Nagarkar NM

Journal: Journal of Otorhinolaryngology, Hearing and Balance Medicine

Published: 2023

Additional Details: 4(2):11

43. Endoscopic Sellar Defect Reconstruction with Avascular Modified Gasket Seal Technique for Sellar Tumors

Authors: Rao KN, Arora RD, Sharma A, Mehta R, Satpute S, Dange P, Nagarkar NM

Journal: Indian Journal of Surgical Oncology

Published: 2024 Mar

Additional Details: 15(1):71-7

44. Survival Outcomes in T3 Laryngeal Cancers: Primary Total Laryngectomy vs

Authors: Rao KN*, Pai PS, Dange P, Kowalski LP, Strojan P, Mäkitie AA, Guntinas-Lichius O, Robbins KT, Rodrigo JP, Eisbruch A, Takes RP

Journal: Concurrent Chemoradiation or Radiation Therapy—A Meta-Analysis. Biomedicines

Published: 2023 Aug

Additional Details: 11(8):2128

45. Observational Learning in Surgical Skill Development

Authors: Rao KN*, Arora RD, Singh A, Dange P, Nagarkar NM

Journal: Indian Journal of Surgical Oncology

Published: 2023 Jul 10

Additional Details: 1-5

46. Hungry Bone Syndrome Following Parathyroidectomy: a Comprehensive Systematic Review of Risk Factors

Authors: Mehta R, Rao KN*, Nagarkar NM, Ghosh A, Sakale H

Journal: Indian Journal of Surgery

Published: 2023 Jun 27

Additional Details: 1-3

47. A Comparison of Harmonic Scalpel and Conventional Techniques for Thyroidectomy

Authors: Arora RD, Prajwal SD, Rao KN, Singh A, Nagarkar NM, Abishek AP

Journal: Indian Journal of Otolaryngology and Head & Neck Surgery

Published: 2023 Jun 24

Additional Details: 1-5

48. Standardizing the Head and Neck Cancer Treatment and Research

Authors: Rao KN*, Arora RD, Dange P, Nagarkar NM

Journal: Indian Journal of Surgical Oncology

Published: 2023 Jun 30

Additional Details: 1-4

49. NLP AI Models for Optimizing Medical Research: Demystifying the Concerns

Authors: Rao KN*, Arora RD, Dange P, Nagarkar NM

Journal: Indian Journal of Surgical Oncology

Published: 2023 Jul 3

Additional Details: 1-5

50. Misconducts in research and methods to uphold research integrity

Authors: Rao KN, Mair M, Arora RD, Dange P, Nagarkar NM

Journal: Indian Journal of Cancer

Published: 2024

Additional Details: 10-4103

51. Emergency Tracheostomy in Locally Advanced Anaplastic Thyroid Cancer

Authors: Arora RD, Rao KN*, Satpute S, Mehta R, Dange P, Nagarkar NM, Abishek AP

Journal: Indian Journal of Surgical Oncology

Published: 2023 Apr 26

Additional Details: 1-9

52. Outcomes of open fronto-facial resection for fungal osteomyelitis of frontal bone

Authors: Mehta R, Rao KN, Nagarkar NM, Sharma A, Kumar B, Karthik P

Journal: Rambam Maimonides Medical Journal

Published: 2022 Oct

Additional Details: 13(4)

53. Pharyngocutaneous fistula following primary total laryngectomy: a meta-analysis

Authors: Rao KN, Arora RD, Singh A, Nagarkar NM, Aggarwal A

Journal: Indian Journal of Surgical Oncology

Published: 2022 Dec

Additional Details: 13(4):797-808

54. Revision Thyroid Surgery

Authors: Rao KN*, Satpute S, Nagarkar NM, Singh A

Journal: Indian Journal of Surgical Oncology

Published: 2021 Nov 4

Additional Details: 1-9

55. Molecular Insights into Oral Malignancy

Authors: Deshmukh A, Rao KN, Arora RD, Nagarkar NM, Singh A, Shetty OS

Journal: Indian Journal of Surgical Oncology

Published: 2022 Jun

Additional Details: 13(2):281

56. Multidisciplinary management of COVID-associated mucormycosis syndemic in India

Authors: Mehta R, Nagarkar NM, Jindal A, Rao KN*, Nidhin SB, Arora RD, Sharma A, Wankhede A, Satpute S, Chakravarty S, Agrawal NK

Journal: Indian Journal of Surgery

Published: 2021 Oct 6

Additional Details: 1-9

57. Transoral Robotic Surgery

Authors: Rao KN*, Gangiti KK

Journal: Indian Journal of Surgical Oncology

Published: 2021 Sep 9

Additional Details: 1-7

58. Free Flap Reconstruction and Its Management in Sickle Cell Trait: Lessons Learned from a Case

Authors: Mehta R, Rao KN*, Nagarkar NM, Aggarwal A

Journal: Indian Journal of Surgical Oncology

Published: 2021 Dec

Additional Details: 12(4):816-21

59. Advanced thyroid cancer controversy and consensus

Authors: Rao K, Deshmukh A, Pai P, Pantvaidya G

Journal: Indian Journal of Medical and Paediatric Oncology

Published: 2020 Jul

Additional Details: 41(04):476-80

60. Management of the neck in oral cancers

Authors: Pantvaidya G, Rao K, D'Cruz A

Journal: Oral Oncology

Published: 2020 Jan 1

Additional Details: 100:104476

61. Impacted incus foreign body in the Eustachian tube

Authors: Parelkar K, Shere D, Wallic A, Dave V, Rao K

Journal: Iranian Journal of Otorhinolaryngology

Published: 2019 Mar

Additional Details: 31(103):123

62. “Implication of surgical loupes on complications following thyroidectomy: a meta-analysis.” European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 10.1007/s00405-024-09003-2

Authors: Rao, Karthik N et al

Journal: 7 Oct

Published: 2024,

63. Bayesian networks to support decision-making for immune-checkpoint blockade in recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC)

Authors: Huehn M, Gaebel J, Oeser A, Dietz A, Neumuth T, Wichmann G, Stoehr M

Journal: Cancers

Published: 2021 Nov 23

Additional Details: 13(23):5890

Languages Spoken

Kannada English Hindi
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